Environmental Adaptations
Zhang,Xumin
Zhang,Xumin, Associate Professor
E-mail:xumin_zhang@fudan.edu.cn
- 1994-1998: Bachelor’s degree and Master’s degree in Biochemistry, Beijing Normal University, Beijing
- 2001-2004: Research Assistant, Beijing Genomics Institute, Chinese Academy of Sciences
- 2004-2008: Ph.D. degree in Proteomics and Biological Mass Spectrometry, University of Southern Denmark
- 02/2008-06/2010: Post-doctoral fellow, University of Southern Denmark
- 10/2010-09/2012: Post-doctoral fellow, Aarhus University
- 03/2013-Now: Associate Professor, School of Life Sciences, Fudan University
Research Interests
Dr. Zhang focuses his research on methodology development in proteomics studies, especially in protein modifications. He also has interests in studying the effects of environmental factors on ageing process using C. elegans.
Selected publications
- Huang J, Wu Z, Wang J, Zhang X*. (2018) Quantitative phosphoproteomics reveals GTBP-1 regulating C.elegans lifespan at different environmental temperatures. Biochem Biophys Res Commun. 503(3):1962-1967
- Wu Z, Huang J, Huang J, Li Q, Zhang X*. (2018) Lys-C/Arg-C, a More Specific and Efficient Digestion Approach for Proteomics Studies. Anal Chem. 90(16):9700-9707.
- Wu Z, Huang J, Lu J, Zhang X*. (2018) Reversible Lysine Derivatization Enabling Improved Arg-C Digestion, a Highly Specific Arg-C Digestion Using Trypsin. Anal Chem. 90(3):1554-1559.
- Huang J, Wang J, Li Q, Zhang Y, Zhang X*. (2018) Enzyme and Chemical Assisted N-Terminal Blocked Peptides Analysis, ENCHANT, as a Selective Proteomics Approach Complementary to Conventional Shotgun Approach. J Proteome Res. 17(1):212-221.
- Zhang Y, Li Q, Huang J, Wu Z, Huang J, Huang L, Li Y, Ye J, Zhang X*.(2018) An Approach to Incorporate Multi-Enzyme Digestion into C-TAILS for C-Terminomics Studies. Proteomics. 18(1). doi: 10.1002/pmic.201700034.
- Ye J, Zhang Y, Huang L, Li Q, Huang J, Lu J, Li Y, Zhang X*. (2016) An optimized guanidination method for large-scale proteomic studies. Proteomics. 16(13):1837-46.
- Zhang Y, He Q, Ye J, Li Y, Huang L, Li Q, Huang J, Lu J, Zhang X*. (2015) Systematic Optimization of C-Terminal Amine-Based Isotope Labeling of Substrates Approach for Deep Screening of C-Terminome. Anal Chem. 87(20):10354-61.