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Ren, Guodong

Ren, Guodong, Professor

E-mail: gdren@fudan.edu.cn

 

 

 

 

 

From 2000 to 2009, Guodong Ren studied biology at Fudan University, where he obtained his bachelor’s degree in Life Sciences in 2004, and Ph.D. degree in Biochemistry and Molecular Biology in 2009. He conducted post-doctoral research at University of Nebraska-Lincoln from 2009 to 2013. He joined Fudan University as an associate professor in Nov. 2013, and promoted to professor in Dec.2014. He works on the genomics, metabolism, and functions of various non-coding RNAs (including microRNAs, siRNAs and lincRNAs) in plants.  

 

Research Interests

1. Small non-coding RNA biogenesis, action and homeostasis.

2. Systemic characterization of long-non-coding RNAs and their functions in plant development and abiotic stress responses.

 

Awards

2014, 1000 Young Talents Plan

2016, Excellent Young Scientists Fund (NSFC)

 

Selected publications

  1. Wang X#, Wang Y#, Dou Y#, Chen L, Wang J, Jiang N, Guo C, Yao Q, Wang C, Liu L, Yu B, Zheng B, Chekanova JA, Ma J, Ren G*. (2018) Degradation of unmethylated miRNA/miRNA*s by a DEDDy-type 3’ to 5’ exoribonuclease ATRIMMER2 in Arabidopsis. PNAS. 115 (28), E6659-E6667 (Direct Submission)
  2. Li Z, Wu S, Chen J, Wang X, Gao J, Ren G* and Kuai B*. (2017), NYEs/SGRs-Mediated Chlorophyll Degradation is Critical for Detoxification during Seed Maturation in Arabidopsis. Plant J. 92(4), 650-661.
  3. Wu S#, Li Z#, Yang L, Xie, Z, Chen J, Zhang W, Liu T, Gao S, Gao J, Zhu Y, Xin J, Ren G*, Kuai B*. (2016) NON-YELLOWING2 (NYE2), a close paralog of NYE1, plays a positive role in chlorophyll degradation in Arabidopsis. Mol Plant. 9(4): 624–627. 
  4. Wang X#, Zhang S#, Dou Y#, Zhang C, Chen X, Yu B*, Ren G*. (2015) Synergistic and independent actions of multiple terminal nucleotidyl transferases in 3’ tailing of small RNAs in Arabidopsis. Plos Genetics. 11(4): e1005091.
  5. Ren G*, Chen X, Yu B*. (2014) Small RNAs meet their targets: when methylation defends miRNAs from uridylation. RNA Biol. 11(9):1099-104.
  6. Ren G#, Xie M#, Zhang S, Vinovskis C, Chen X and Yu B*. (2014) Methylation protects miRNAs from an AGO1-associated activity that uridylates 5' RNA fragments generated by AGO1 cleavage Proc Natl Acad Sci USA. 111 (17), 6365-6370.
  7. Ren G, Chen X, Yu B*. (2012) Uridylation of miRNAs by HEN1 SUPPRESSOR1 in Arabidopsis. Curr Biol. 22(8): 695-700.
  8. Ren G, Xie M, Dou Y, Zhang S, Zhang C, Yu B*. (2012) Regulation of small RNA abundance by TOUGH in Arabidopsis. Proc Natl Acad Sci USA.109(31):12817-12821 (Direct Submission)
  9. Ren G, Yu B*. (2012) Critical roles of RNA-binding proteins in miRNA biogenesis in Arabidopsis. RNA Biol. 9(12):1424-8. 
  10. Xie M#, Ren G#, Zhang C, Yu B*. (2012) The DNA and RNA binding protein FACTOR of DNA METHYLATION 1 requires XH domain-mediated complex formation for its function in RNA-directed DNA methylation. Plant J. 72, 491–500 (#, Equal Contribution)