基本信息

职称：教授
电话：021-51630633
邮箱：aiwudong@fudan.edu.cn
地址：复旦大学生命科学学院 A401-5室

 

 

个人简介

1970年出生，博士，教授。1993，吉林大学生物化学学士；1996年，北京大学生物化学硕士；2003年复旦大学生物化学博士；1996年起，复旦大学生命科学学院任教，现任生物化学系主任。

 

主要研究方向 (Research Interests)

利用生物化学、分子生物学、细胞生物学、遗传学等方法研究植物细胞分裂和生长发育过程中的表观遗传调控机制。主要包括(1)染色质组装与重塑调控植物细胞分裂和生长发育的分子机制， (2)组蛋白甲基化修饰及其识别调节植物生长发育的分子机制。

 

获奖情况 (Awards)

教育部优秀青年教师（2003），上海市青年科技启明星（2003），第四届中国青年女科学家奖（2007），上海市曙光学者（2008），上海市“三八”红旗手（2009）。

 

代表性成果

1. Zhu Y*, Rong L, Luo Q, Wang B, Zhou N, Yang Y, Zhang C, Feng H, Zheng L, Shen WH, Ma J*, Dong A*. (2017) The Histone Chaperone NRP1 Interacts With WEREWOLF to Activate GLABRA2 in Arabidopsis Root Hair Development. Plant Cell. doi: 10.1105/tpc.16.00719.

2. Zhou W, Gao J, Ma J, Cao L, Zhang C, Zhu Y, Dong A*, Shen WH*. (2016) Distinct roles of the histone chaperones NAP1 and NRP and the chromatin-remodeling factor INO80 in somatic homologous recombination in Arabidopsis thaliana. Plant J. 88(3):397-410. doi: 10.1111/tpj.13256.

3. Liu B, Wei G, Shi J, Jin J, Shen T, Ni T, Shen WH, Yu Y*, Dong A*. (2016) SET DOMAIN GROUP 708, a histone H3 lysine 36-specific methyltransferase, controls flowering time in rice (Oryza sativa). New Phytol. 210(2):577-88. doi: 10.1111/nph.13768.

4. Jin J, Shi J, Liu B, Liu Y, Huang Y, Yu Y*, Dong A*. (2015) MRG702, a reader protein of H3K4me3 and H3K36me3, is involved in brassinosteroid-regulated growth and flowering time control in rice.  Plant Physiol. 168(4):1275-85. doi: 10.1104/pp.114.255737.

5. Zhang C, Cao L, Rong L, An Z, Zhou W, Ma J, Shen WH, Zhu Y*, Dong A*. (2015) The chromatin-remodeling factor AtINO80 plays crucial roles in genome stability maintenance and in plant development.  Plant J. 82(4):655-68. doi: 10.1111/tpj.12840.

6. Bu Z, Yu Y, Li Z, Liu Y, Jiang W, Huang Y, Dong A*. (2014) Regulation of Arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. PLoS Genet. 10(9):e1004617. doi: 10.1371/journal.pgen.1004617.

7. Weng M, Yang Y, Feng H, Pan Z, Shen WH, Zhu Y*, Dong A*. (2014) Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana. Plant Cell Environ. 37(9):2128-38. doi: 10.1111/pce.12299.

8. Sui P, Shi J, Gao X, Shen WH, Dong A*. (2013) H3K36 methylation is involved in promoting rice flowering. Mol Plant. 6(3):975-7. doi: 10.1093/mp/sss152.

9. Li Z, Li B, Shen WH, Huang H, Dong A*. (2012) TCP transcription factors interact with AS2 in the repression of class-I KNOX genes in Arabidopsis thaliana. Plant J. 71(1):99-107. doi: 10.1111/j.1365-313X.2012.04973.x.

10. Sui P, Jin J, Ye S, Mu C, Gao J, Feng H, Shen WH, Yu Y*, Dong A*. (2012) H3K36 methylation is critical for brassinosteroid-regulated plant growth and development in rice. Plant J. 70(2):340-7. doi: 10.1111/j.1365-313X.2011.04873.x.

11. Li Z, Li B, Dong A*. (2012) The Arabidopsis transcription factor AtTCP15 regulates endoreduplication by modulating expression of key cell-cycle genes. Mol Plant. 5(1):270-80. doi: 10.1093/mp/ssr086.

12. Zhu Y, Weng M, Yang Y, Zhang C, Li Z, Shen WH*, Dong A*. (2011) Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development. Plant J. 66(3):443-55. doi: 10.1111/j.1365-313X.2011.04504.x.